Topical Diltiazem Versus Topical Glyceryl Trinitrate In The Management Of Chronic Anal Fissure

Topical Diltiazem versus topical Glyceryl trinitrate (GTN) in the treatment of chronic anal fissure: Prospective study

Topical diltiazem hydrochloride and glyceryl trinitrate in the treatment of chronic anal fissure.

OBJECTIVE To compare the symptomatic relief, healing and side-effects of topical diltiazem (DTZ) and glyceryl trinitrate in the treatment of chronic anal fissure. STUDY DESIGN Randomized controlled trial. PLACE AND DURATION OF STUDY The Surgical Outpatient Department of Civil Hospital, Karachi, from March 2006 to February 2007. METHODOLOGY Patients with chronic anal fissure were included ...

Topical glyceryl trinitrate in the treatment of anal fissure.

AIM the aim of this study was to assess the effectiveness of topical glyceryl trinitrate (GTN) in the treatment of anal fissure. PATIENTS eighty consecutive patients were randomized to receive 0.2% GTN gel twice a day during a minimum of 6 weeks. Of these 80 patients 34 were males and 46 female, with ages between 20 and 78 years. All patients underwent a work-up that included gender, age, sym...

Diltiazem (2%) versus glyceryl trinitrate cream (0.2%) in the management of chronic anal fissure.

OBJECTIVE To assess and compare the effectiveness of topical 0.2% glycerl trinitrate (GTN) and topical 2% diltiazem (DTZ), in the management of chronic anal fissure. STUDY DESIGN Comparative, descriptive study. PLACE AND DURATION OF STUDY Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad from September 2004 to August 2005. METHODOLOGY Patients wi...

Establishing the Superiority of Topical Diltiazem over Glyceryl Trinitrate in the Treatment of Chronic Anal Fissure: a Prospective Analytical Study

Introduction: Anal fissure is a common ailment of young age group, affecting males and females alike. Traditionally surgery has been the 1st line of treatment but recently the topical agents such as Glyceryl Trinitrate and Diltiazem are replacing the surgical treatment as preferred modality. Objective: The present study was conducted to compare the topical GTN and DTZ in terms of effectiveness,...